Detection of Cytological changes in buccal mucosa among Sudanese alcohol drinkers

Alkhair Abd Almahmoud Idris; Mohammed Abuzied Mustafa; Hassan Moutasim Yousif; Mohammed Aldai Hammad; Mohammed Abdelgader Elsheikh

doi:10.5455/JBRR.20241008021709

Abstract
Aim:
Chronic alcohol consumption led to a number of cytological changes in mouth including inflammatory cell, fungal infection, bacterial infection, viral infection, dyskaryosis and the malignant changes. The study aimed to detect the cytological changes of buccal mucosa causing by alcohol consumptions.
Methods:
This was laboratory-based study included a total number of 50 patients of alcohol consumptions and 25 non-alcohol drinkers of which were collected from healthy people. Samples collected were two buccal smears from buccal mucosa of alcohol consumers, using tongue depressor, before that washed mouth to avoid contamination of bacteria.
Results:
The results of this study were based on cytological analysis. The highest frequency of age groups was 20(40%). The most percentage of inflammatory change in age groups (51-60) was (45%).
The cytological findings showed in study population, the normal result there was (28%) but the inflammatory changes show is very significant was (60%) while the infected changes and dyskaryosis not significant was (6%) for each.
Conclusions:
This descriptive laboratory study confirmed the effectiveness of alcohol on buccal mucosa which led to abnormality of cytological findings like inflammatory changes, infected changes, dyskaryosis and malignant changes due to excessive alcohol intake.

Key words: Dyskaryosis. malignant changes, alcohol intake, Sudan